md-medicaldata

Authors

Marko Brkić¹, Saša Jović^1,3, Ružica Kozomara^1,3, Milka Gardašević¹, Uroš Marjanović¹, Miroslav Broćić¹, Stanislava Petrović¹, Nikola Đurđević¹, Gordana Šupić^2,3, Srboljub Stošić<sup>1,3

1</sup>Clinic for Maxillofacial Surgery, Military Medical Academy, Belgrade,
²Institute for Medical Research, Military Medical Academy, Belgrade,
³Faculty of Medicine, Military Medical Academy, University of Defence, Belgrade, Serbia

 

UDK: 617.52-006.3-089

The paper was received / Rad primljen 07.08.2025.

Accepted / Rad prihvaćen: 13.08.2025.

 

Correspondence to:

prof. dr Ružica Kozomara
e-mail: ruzicakozomara@yahoo.com

 

 

Abstract

 

 

In this article presented a 42-year-old patient who underwent multiple operations for locally aggressive dermatofibrosarcoma protuberance of the face at the Maxillofacial Surgery Clinic of the Military Medical Academy in Belgrade. A patient with an extremely aggressive form of dermatofibrosarcoma protuberance of the middle third of the face who was operated on seven times in two years is presented. He was operated four times for an extremely large tumor (size about 200x120cm), which first grew to that size within just one month and recurred within a short period of time after each operation. Dermatofibrosarcoma protuberans is a locally aggressive tumor and can have a rapid and destructive course, which generally has no metastatic potential, and surgical treatment is considered the best modality of treatment. Due to the pronounced local aggressive behavior, this form of tumor can often be completely removed surgically. That is why a wide local excision with margins of 3-5 cm towards healthy tissue is suggested today, as well as resection of deep structures, including bone. In patients with recurrent tumors, the best result that can contribute to successful surgical treatment involves wide resection margins of soft and bone tissues, regardless of functional and aesthetic consequences.

 

Key words:

Dermatofibrosarcoma protuberans, dermatofibroma, wide excision

 

 

 

Sažetak

 

U radu je prikazan 42- godišnji pacijent koji je u više navrata operisao lokalno agresivni dermatofibrosarkoma protuberans lica u Klinici za Maksilofacijalnu hirurgiju Vojnomedicinske akademija u Beogradu. Prikazan je pacijent sa izuzetno agresivnim oblikom dermatofibrosarkoma protuberans srednje trećine lica koji je operisan sedam puta u dve godine. Četiri puta je operisan zbog izuzetno velikog tumora (veličine oko 200x120cm), koji je prvi put nastao do te veličine u roku od samo mesec dana i isti se ponovo javio u kratkom vremenskom periodu nakon svake operacije. Dermatofibrosarkom protuberans je lokalno agresivan tumor i može imati brz i destruktivan tok, koji uglavnom nema metastatski potencijal te se hirurško lečenje smatra najboljim modalitetom lečenja. Zbog izraženog lokalno agresivnog ponašanja često se ovaj oblik tumora može hirurški u celosti ukloniti. Zato se danas predlaže široka lokalna ekscizija sa marginama od 3-5 cm prema zdravom tkivu, kao i resekcija dubokih struktura, uključujući i kost. Kod pacijenata sa rekurentnim tumorom najbolji rezulat koji može doprineti uspešnom hirurškom lečenju podrazumeva široke margine resekcije mekih i koštanih tkiva bez obzira na funkcionalne i estetske posledice.

 

Ključne reči:

Dermatofibrosarcoma protuberans, dermatofibrom, margine resekcije tumora

 

 

 

 

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